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Stroke Data Bank definitions ensured more transient ischemic attacks in atherosclerotic infarcts and more cardiac disease in cardioembolic infarcts,but the diagnosis was distinguished further using a logistic regression model.Fractional arm weakness(shoulder different from hand) (odds ratio 3.1,95%confidence interval[CI]1.6-5.8),hypertension(odds ratio 2.8,CI 1.4-5.3),diabetes(odds ratio 2.5,CI 1.2-5.1)and male gender(odds ratio=2.2,CI 1.2-4.1)occurred more frequently in patients with atherosclerotic than cardioembolic infarcts.Reduced consciousness(odds ratio=3.2,CI 1.4-7.3)was more frequent in cardioembolism.For a male patient with hypertension,diabetes,and fractional arm weakness,the estimated odds of an atherosclerotic infarction were 47-fold that of a cardioembolic infarction.Patients with atherosclerotic infarcts were more likely to have a fractional arm weakness regardless of infarct size, whereas,for those with cardioembolic infarctions,fractional weakness was more frequent in infarcts less than 20 cc in volume.Conclusions:Clinical features that are observed at stroke onset can help distinguish cerebral infarction subtypes and may allow for early stratification in therapeutic trials. |
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carotid artery atherosclerosis
carotid artery disease
carotid artery stenosis
cerebral embolism
cerebral embolism,cardiac origin
cerebrovascular accident
cerebrovascular accident,clinical diagnosis
cerebrovascular disease,risk factors in
embolism
level of consciousness,decreased
neurologic disease,diagnoses of
neurologic disease,diagnoses of,clinical bedside
neurologic examination
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